Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs). In ...

The complex ‘language’ of plant RNA encodes a vast array of biological regulatory elements that orchestrate crucial aspects of plant growth, development and adaptation to environmental stresses.

Small-molecule compounds that elicit mRNA-selective translation repression have attracted interest due to their potential for expansion of druggable space. However, only a limited number of examples ...