DNA methylation has become one of the hottest targets in modern biomedicine. The chemical tags that adorn cytosine bases ...

A simple blood draw that reads chemical tags on DNA shed by tumors has delivered a strikingly better performance than the ...

A study suggests blood DNA methylation patterns could identify increased prostate cancer risk years before diagnosis. Read ...

Researchers led by the University of Ulsan College of Medicine, Korea, have checked the performance of a noninvasive urinary DNA methylation test for bladder cancer diagnosis. Findings indicate that ...

Researchers found that genome-wide plasma cfDNA methylation profiles collected before diagnosis contained early molecular ...

Interest in longevity science and precision health has driven attention toward epigenetic testing, which provides a deeper understanding of biological age compared to traditional lab assessments.

The test involves using a dedicated chip and fluorescence analysis, in which fragments of cell-free DNA in the blood are ...

A study of blood samples collected up to nine years before a cancer diagnosis found changes in the DNA that captured the body ...

DNA methylation is an epigenetic modification in which a methyl group is added to a DNA base without changing the underlying DNA sequence. In mammals, the best-known form is 5-methylcytosine (5mC), ...

Spontaneous epimutations are stochastic gains and losses of cytosine methylation that arise from imperfect maintenance across cell divisions. At CG sites, such epimutations can be inherited across ...

Alzheimer’s disease (AD) is driven by genetic and epigenetic factors. A knowledge gap remains in applying DNA methylation (DNAm) to capture AD-specific signatures. We developed the AD DNA Methylation ...