C&EN

Suppressor tRNAs restore full-length dystrophin in mice with Duchenne muscular dystrophy

The new study reports the development of suppressor tRNAs that have been optimized to target UAA stop codons, which arise when a glutamine CAA is mutated. The suppressor tRNA reads UAA as glutamine ...

[Python x Drug Discovery AI] Building a Mathematical Prediction and Codon Optimization Pipeline for Personalized Cancer mRNA Vaccines from Scratch

IntroductionIn recent years, mRNA technology, which gained sudden prominence with the COVID-19 vaccine, is now poised to ...
ascopubs.org

Comparison of the characteristics and clinical course of 677 patients with metastatic lung cancers with mutations in KRAS codons 12 and 13.

RET rearrangements detected by FISH in “pan-negative” lung adenocarcinoma. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a full text component.